The main character, Emily, is the one that the doctor, Benway, focuses on. She is a young girl who at one point was in med school, and the doctor seems to focus on this about her. He tells her she should go back to med school and get her degree, but he isn't who he seems to be, and behind the scenes he is experimenting, on what the audience doesn't really know.
One by one Emily's friends are taken away to be examined, and treated like experiments. She doesn't know what is happening until the doctor starts asking her some very odd questions during her exam. Emily asks after her boyfriend, Bobby, and is constantly told that he is in recovery, but towards the end of the movie she finds that nothing is that simple.
I will once again be honest, this was not the best movie. There was no explanation of plot, and as a horror movie it wasn't scary. It tries too hard to be a grotesque horror movie with violence and blood, but that isn't what makes a movie a horror movie. A good horror movie has something frightening, it suspends belief and makes one want to watch more. A good horror movie makes one sit on the edge of their seat and anxiously wait to see what happens to the characters. This movie had none of that.
I didn't get to know the backstory of any of the characters, which doesn't help make me care what happens to them. The bad guy, Dr. Benway, wasn't at all scary or menacing (even though the character was played by the excellent Robert Patrick). The scares were mostly of the gore and blood type, showing the inside of a characters beaten skull as another character tries to help them isn't scary, it is just dull since it has been done over and over. The movie just didn't grab me like it should have and I found my mind drifting to other things. It was boring, which is a bad thing for a horror movie to be.
I don't recommend this movie to anyone, not even anyone like me who will watch anything (even when it has bad reviews from others). It was dull, unoriginal, and just bland.